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Development of Modern Low Altitude Air-defence Missile Weapon System

Zhong Shan

Strategic Study of CAE 2001, Volume 3, Issue 5,   Pages 1-11

Abstract:

The analyses of characteristic parameters of modern low altitude air-defence missile weapon systemThe synthetical evaluation of several foreign low altitude air-defence missile weapon systems is madeAt the end of this paper the development tendency of weapon system in future is discussed in accordance

Keywords： air-defence missile     weapon system     characteristic parameters     specification of the tactics and technicality    

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Particle therapy for cancers: a new weapon in radiation therapy

Guo-Liang Jiang

Frontiers of Medicine 2012, Volume 6, Issue 2,   Pages 165-172 doi: 10.1007/s11684-012-0196-4

Abstract:

Particle irradiation started to draw attention in the past decade and has now become a hotspot in the radiation oncology community. This article reviews the most advanced developments in particle irradiation, focusing on the characteristics of proton and carbon ions in radiation physics and radiobiology. The Bragg peak of physical dose distribution causes proton and carbon beams to optimally meet the requirement for cancer irradiation because the Bragg peak permits the accurate concentration of the dose on the tumor, thus sparing the adjacent normal tissues. Moreover, carbon ion has more radiobiological benefits than photon and proton beams. These benefits include stronger sterilization effects on intrinsic radio-resistant tumors and more effective killing of hypoxic, G0, and S phase cells. Compared with the most advanced radiation techniques using photon, such as three-dimensional conformal radiation therapy and intensity-modulated radiation therapy, proton therapy has yielded more promising outcomes in local control and survival for head and neck cancers, prostate carcinoma, and pediatric cancers. Carbon therapy in Japan showed even more promising results than proton therapy. The local controls and overall survivals were as good as that treated by surgery in early stages of non-small cell lung cancer, hepatocellular carcinoma, prostate carcinoma, and head and neck cancers, especially for such highly resistant tumors as melanoma. The non-invasive nature of particle therapy affords more patients with chances to receive and benefit from treatment. Particle therapy is gradually getting attention from the oncology community. However, the cost of particle therapy facilities has limited the worldwide use of this technology.

Keywords： radiation therapy     particle therapy     proton     carbon     cancer    

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CAR T-cell immunotherapy: a powerful weapon for fighting hematological B-cell malignancies

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 783-804 doi: 10.1007/s11684-021-0904-z

Abstract: The current standard of care in hematological malignancies has brought considerable clinical benefits to patients. However, important bottlenecks still limit optimal achievements following a current medical practice. The genetic complexity of the diseases and the heterogeneity of tumor clones cause difficulty in ensuring long-term efficacy of conventional treatments for most hematological disorders. Consequently, new treatment strategies are necessary to improve clinical outcomes. Chimeric antigen receptor T-cell (CAR T) immunotherapy opens a new path for targeted therapy of hematological malignancies. In this review, through a representative case study, we summarize the current experience of CAR T-cell therapy, the management of common side effects, the causative mechanisms of therapy resistance, and new strategies to improve the efficacy of CAR T-cell therapy.

Keywords： CAR T cells     hematological malignancies     review    

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Study on Acquisition Risk Identification for Weapon and Equipment Based on the Full Life Cycle

Li Zhongmin,,Tang Shuchun,Li Jun4,Chen Jian

Strategic Study of CAE 2005, Volume 7, Issue 12,   Pages 49-53

Abstract:

Risk identification is the key technology of acquisition risk management for weapon and equipment.It has a direct and essential effect on the success of acquisition risk management for weapon and equipmentIn the end, the paper analyzes the risk in every phase of the weapon and equipment's full life cycleAll of this plays a basic role in the systematic management of acquisition risk for weapon and equipment

Keywords： risk identification     acquisition risk management for weapon and equipment     the full life cycle    

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The Application of Risk Matrix to Acquisition Risk Evaluation for Weapon and Equipment

Li Zhongmin,Wei Yiming,Tang Shuchun,Chen Jian

Strategic Study of CAE 2006, Volume 8, Issue 6,   Pages 95-99

Abstract:

Risk evaluation is the basis of acquisition management for weapon and equipment.abroad, the paper firsdy discusses the application of risk matrix in acquisition risk evaluation for weaponbeginning with the two rules of risk impact and risk probability, demonstrates risk evaluation of a type of weapon

Keywords： risk matrix     risk evaluation     acquisition for weapon and equipment    

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Earth-penetrating Weapons and Their Experiments Upon Gas Gun

Lin Junde

Strategic Study of CAE 2003, Volume 5, Issue 11,   Pages 25-33

Abstract:

The history and the actualities of developing earth-penetrating weapon are described.The experimental technique of gas gun and its applications in earth-penetrating weapon tests are introduced

Keywords： test of weapon     earth penetrating     gas gun     impact     experimental technique    

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Study on evaluation method of weapon equipment readiness

Yu Xiang,Du Gang and He Qiwei

Strategic Study of CAE 2015, Volume 17, Issue 5,   Pages 76-82

Abstract:

Weapon equipment readiness evaluation is important for the meticulous and scientific usage managementand maintenance support of weapon equipment.Therefore， an improved evaluation method for weapon equipment readiness based on the technical status

Keywords： equipment readiness；technical status；maintenance support of equipment；countermeasures    

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Development Trends of Chemical and Biological Weapons and Defense Technology in the 21st Century

Chen Jisheng

Strategic Study of CAE 2000, Volume 2, Issue 11,   Pages 25-28

Abstract: The rapid progress in biotechnology and other related R&D may provide new change in CB weapon technologies

Keywords： chemical and biological weapon     chemical and biological defense     medical protection     chemical and biological    

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A New Multifunction Lube Oil for Weapons with Excellent Performances in Cleaning, Lubricating and Protecting

Feng Weisun,Wang Mengyan

Strategic Study of CAE 2000, Volume 2, Issue 4,   Pages 53-58

Abstract:

The multifunction oil for weapons is a unique product with excellent performances used in military forces of ground, navy and air under various climate conditions. As for its multiple performances the product needs excellent base oil with more kinds of additives. Among them there may be some synergistic or negative interactions that need to be well balanced. During the study various effects were investigated. Finally all the main problems were settled down and the lube oil for weapons with excellent performances in cleaning, lubricating and protecting was obtained.

Keywords： multifunction weapon oil     base oil     additive     cleaning     lubricating     protecting    

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System reliability and system resilience

Frontiers of Engineering Management 2021, Volume 8, Issue 4,   Pages 615-619 doi: 10.1007/s42524-021-0176-y

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Engineering, Engineering System, Engineering System Theory, and System of Engineering Science

Wang Liancheng

Strategic Study of CAE 2001, Volume 3, Issue 6,   Pages 15-18

Abstract: of basic contents, nature and feature of engineering, this paper introduces concepts of engineering systemand engineering system theory, then discusses objects of study and research methods of engineering systemtheory using thinking of general system theory.Finally, it expounds meta-discipline standing of engineering system theory in system of engineering science

Keywords： engineering     system     system theory     discipline    

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Cyber–Physical Power System (CPPS): A review on measures and optimization methods of system resilience

Frontiers of Engineering Management 2021, Volume 8, Issue 4,   Pages 503-518 doi: 10.1007/s42524-021-0163-3

Abstract: The Cyber–Physical Power System (CPPS) is one of the most critical infrastructure systems in a country

Keywords： Cyber–Physical Power System     resilience assessment     resilience optimization     cascading failure modeling    

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Discussion on the System Optimization of the Energy Development Strategy and Plan

Da-di Zhou

Frontiers of Engineering Management 2014, Volume 1, Issue 2,   Pages 147-152 doi: 10.15302/J-FEM-2014022

Abstract: Due to the complexity of the energy system, the interactive relationship with economic and social development, and the enormous investment involved, the optimization of the energy system is of great significanceefforts to develop targets and specific approaches for the rational and optimal development of an energy system

Keywords： energy development strategy     planning system     system optimization    

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Distributed monitoring and diagnosis system for hydraulic system of construction machinery

Xiaohu CHEN, Wenfeng WU, Hangong WANG, Yongtao ZHOU,

Frontiers of Mechanical Engineering 2010, Volume 5, Issue 1,   Pages 106-110 doi: 10.1007/s11465-009-0089-7

Abstract: This paper mainly presents a distributed monitoring and diagnosis system for the hydraulic system ofThe hardware of the distributed condition monitoring and fault diagnosis system is designed.experiments and applications indicate that the distributed condition monitoring and fault diagnosis systemrealize its function of real-time online condition monitoring and fault diagnosis for the hydraulic system

Keywords： construction machinery     hydraulic system     distributed condition monitoring     controller area net (CAN) field    

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Theory and method of mechanism system design

Huijun ZOU, Qinghua LIANG, Qing ZHANG

Frontiers of Mechanical Engineering 2010, Volume 5, Issue 4,   Pages 399-411 doi: 10.1007/s11465-010-0116-8

Abstract: Conceptual design is the most critical and creative phase of design. Recently, increasing attention has been directed to supporting conceptual-level computer aided creative design and its theories and methodologies. Specifically, for conceptual design of mechanical products, this paper presents a novel function solving model for mechanical product design and highlights the importance of systematic synthesis to achieve creative design. Then it builds a framework as a function-effect-process-action- mechanisms (FEPAM) mapping process, which enables creative design on the basis of conceiving different action schemes. After that, several key points are elaborated including 1) representing and decomposition methods of functions and motion behaviors; 2) action scheme representing method based on network plan techniques; and 3) variation and creation methods based on action scheme transformations.

Keywords： mechanism system creative design     process model     function solving model     process action procedure     mechanismsknowledge base     principle of mechanism system composition    

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Title Author Date Type Operation

Development of Modern Low Altitude Air-defence Missile Weapon System

Zhong Shan

Journal Article

Particle therapy for cancers: a new weapon in radiation therapy

Guo-Liang Jiang

Journal Article

CAR T-cell immunotherapy: a powerful weapon for fighting hematological B-cell malignancies

Journal Article

Study on Acquisition Risk Identification for Weapon and Equipment Based on the Full Life Cycle

Li Zhongmin,,Tang Shuchun,Li Jun4,Chen Jian

Journal Article

The Application of Risk Matrix to Acquisition Risk Evaluation for Weapon and Equipment

Li Zhongmin,Wei Yiming,Tang Shuchun,Chen Jian

Journal Article

Earth-penetrating Weapons and Their Experiments Upon Gas Gun

Lin Junde

Journal Article

Study on evaluation method of weapon equipment readiness

Yu Xiang,Du Gang and He Qiwei

Journal Article

Development Trends of Chemical and Biological Weapons and Defense Technology in the 21st Century

Chen Jisheng

Journal Article

A New Multifunction Lube Oil for Weapons with Excellent Performances in Cleaning, Lubricating and Protecting

Feng Weisun,Wang Mengyan

Journal Article

System reliability and system resilience

Journal Article

Engineering, Engineering System, Engineering System Theory, and System of Engineering Science

Wang Liancheng

Journal Article

Cyber–Physical Power System (CPPS): A review on measures and optimization methods of system resilience

Journal Article

Discussion on the System Optimization of the Energy Development Strategy and Plan

Da-di Zhou

Journal Article

Distributed monitoring and diagnosis system for hydraulic system of construction machinery

Xiaohu CHEN, Wenfeng WU, Hangong WANG, Yongtao ZHOU,

Journal Article

Theory and method of mechanism system design

Huijun ZOU, Qinghua LIANG, Qing ZHANG

Journal Article